6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl]
![6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] Cov duab tshwj xeeb](http://cdn.globalso.com/jindunchem-med/0ecf55f0.jpg)
6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl]
Cov khoom no yog lub teeb daj zaj duab xis-coated ntsiav tshuaj, dawb los yog yuav luag dawb tom qab tshem tawm cov txheej.
Cov lus qhia
Cov khoom no tsim nyog rau kev kho mob ntshav qab zib hom 2.
Monotherapy
Cov khoom no yog siv nrog kev tswj hwm kev noj haus thiab kev tawm dag zog los txhim kho cov ntshav qab zib hauv cov neeg mob ntshav qab zib hom 2.
Siv ua ke nrog metformin hydrochloride
Thaum metformin hydrochloride ib leeg tsis tuaj yeem tswj cov ntshav qab zib kom zoo, cov khoom no tuaj yeem siv ua ke nrog metformin hydrochloride txhawm rau txhim kho cov ntshav qab zib hauv cov neeg mob ntshav qab zib hom 2 raws li kev noj haus thiab kev tawm dag zog.
Siv ua ke nrog metformin hydrochloride thiab sulfonylureas.
Thaum kev sib xyaw ua ke ntawm metformin hydrochloride thiab sulfonylureas tsis tuaj yeem tswj cov ntshav qab zib kom zoo, cov khoom no tuaj yeem siv ua ke nrog metformin hydrochloride thiab sulfonylureas los txhim kho cov ntshav qab zib tswj cov neeg mob ntshav qab zib hom 2 raws li kev noj haus thiab kev tawm dag zog.
Kev txwv tshuaj
Cov khoom no tsis pom zoo rau cov neeg mob ntshav qab zib hom 1 lossis kev kho mob ntshav qab zib ketoacidosis.
Specification
(1) 10 mg;(2) 25 mg.
Kev noj tshuaj
Pom zoo koob tshuaj.
Qhov pom zoo koob tshuaj ntawm cov khoom no yog 10 mg thaum sawv ntxov, ib zaug ib hnub, ntawm lub plab khoob lossis tom qab noj mov.Hauv cov neeg mob uas zam cov khoom no, cov koob tshuaj tuaj yeem nce mus rau 25 mg (saib [Clinical Trials]).
Hauv cov neeg mob hypovolemia, nws raug nquahu kom kho cov hypovolemia ua ntej pib siv cov khoom no (saib [Kev Ceeb Toom]).
Cov neeg mob raum tsis zoo.
Nws raug nquahu kom ntsuas lub raum ua haujlwm ua ntej pib siv cov khoom no, thiab tom qab ntawd nws yuav tsum tau soj ntsuam tsis tu ncua.
Cov neeg mob uas eGFR qis dua 45 mL / min / 1.73 m2 yuav tsum tsis txhob siv cov khoom no.
Cov neeg mob uas muaj eGFR siab dua lossis sib npaug li 45 mL / min / 1.73 m2 tsis tas yuav kho qhov koob tshuaj.
Yog tias eGFR tsis tu ncua qis dua 45 mL / min / 1.73 m2, cov khoom no yuav tsum raug txiav tawm (saib [Kev Ceeb Toom]).
Cov neeg mob lub siab puas tsuaj.
Cov neeg mob uas lub siab puas tsuaj tsis tas yuav kho cov koob tshuaj.Enpagliflozin raug nce ntxiv hauv cov neeg mob uas mob siab heev.Kev paub txog kev kho mob ntawm cov neeg mob uas muaj daim siab mob hnyav yog txwv, yog li ntawd, nws tsis pom zoo rau qhov no ntawm cov pejxeem.
Txheem:tus qauv kev lag luam
purity:≥99.0%
Sab nrauv:dawb mus rau dawb hmoov
Pob:25kg / nruas
JIN DUN Medical muajISO tsim nyog thiab ua tau raws li GMP cov qauv tsim, ua hauj lwm hauv tsev thiab txawv teb chaws cov kws kho tshuaj synthesis nrog kev nplua nuj los coj lub tuam txhab R & D.
TECHNOL OGY ADVANTAGES
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction.Cryogenic cov tshuaj tiv thaiv (<-78% C)
●Aromatic Heterocyclic Synthesis
● Kev Ruaj Ntseg Tsis Zoo
● Chiral Resolution
●Heck, Suzuki, Negishi, Sonogashira .Gignard Reaction
Cov khoom siv
Peb lub Lab muaj ntau yam kev sim thiab ntsuas cov cuab yeej, xws li: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope ...
Pab neeg R&D
Jindun Kev Kho Mob muaj ib pab pawg kws tshaj lij R & D cov neeg ua haujlwm, thiab ntiav ntau tus kws tshaj lij kev siv tshuaj hauv tsev thiab txawv teb chaws los coj R&D, ua rau peb cov khoom sib xyaw ua kom raug thiab ua tau zoo.
Peb tau pab ntau lub tuam txhab tshuaj hauv tsev sab saum toj, xws liHansoh, Hengrui thiab HEC Pharm.Ntawm no peb yuav qhia ib feem ntawm lawv.
Customzation Case Ib:
CAS Nr .: 110351-94-5
Customzation Case Ob:
CAS Nr .: 144848-24-8
Customzation Case Peb:
CAS Nr .: 200636-54-0
1.Customize New Intermediates lossis APIs.Ib yam li cov ntaub ntawv sib qhia saum toj no, cov neeg siv khoom muaj qhov xav tau tshwj xeeb Intermediates lossis APIs, thiab lawv nrhiav tsis tau cov khoom xav tau hauv khw, ces peb tuaj yeem pab kho.
2.Txheej txheem Optimization rau cov khoom qub.Peb pab neeg yuav pab Optimize thiab txhim kho xws li ntau lawm uas nws cov tshuaj tiv thaiv txoj kev yog qub, ntau lawm nqi yog siab, thiab efficiency yog tsawg.Peb tuaj yeem muab cov ntaub ntawv tag nrho rau kev hloov pauv thev naus laus zis thiab kev txhim kho cov txheej txheem, pab cov neeg siv khoom kom muaj txiaj ntsig ntau dua.
Los ntawm cov hom phiaj tshuaj rau INDs, JIN DUN Kev Kho Mob muab rau kojib-nres tus kheej R & D kev daws teeb meem.
JIN DUN Kev Kho Mob hais kom tsim ib pab neeg nrog kev npau suav, ua cov khoom muaj txiaj ntsig, ua kom zoo, nruj, thiab tawm mus ua ib tus neeg ntseeg siab thiab phooj ywg ntawm cov neeg siv khoom!
