2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethane

2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone yog siv los ua qhov nruab nrab ntawm Prasugrel.
Prasugrel yog thiophenopyridine antiplatelet tsim los ntawm Eli Lilly thiab daiichisankyo, lub chaw tsim tshuaj Japanese.Nws yog ib qho tshuaj precursor.Nws tsim ib qho active molecule tom qab metabolism los ntawm cytochrome P450 nyob rau hauv lub siab thiab ua ke nrog platelet P2Y12 receptor kom muaj zog tiv thaiv platelet aggregation.Cov kev tshawb fawb soj ntsuam tau ua pov thawj tias 60 mg koob tshuaj muaj cov nyhuv anticoagulant zoo dua li 300 mg tus qauv koob tshuaj thiab 600 mg nce koob tshuaj clopidogrel, uas tuaj yeem txo qhov kev pheej hmoo ntawm lub plawv nres, mob stroke thiab tuag vim mob plawv los ntawm 20%, thiab muaj txiaj ntsig sai. , zoo curative nyhuv, zoo tshuaj kuj thiab bioavailability, thiab tsawg toxicity.