4-Methoxybenzylalkohol; ANISALKOHOL; 4-methoxy-benzenemethano;

Intermediate rau Moxonidine
Muaj peev xwm ua kom lub hauv paus α2 receptors thiab ua rau muaj kev cuam tshuam rau cov ntshav siab, zoo ib yam li clonidine.Qhov nqus ntawm qhov ncauj (90%) thiab bioavailability (88%) yog ob qho tib si siab, thiab tsis muaj qhov cuam tshuam thawj zaug.Cov ntshav siab tshaj plaws tshwm sim 1 mus rau 3 teev tom qab noj cov tshuaj.Feem ntau ntawm nws yog tawm los ntawm lub raum.t1/2 yog li 2 teev.Clinically siv rau kub siab.

Tsis muaj xim los yog kua daj me ntsis.Lub melting point yog 23-25.5 ° C, boiling point yog 159 ° C, tus txheeb ze ceev yog 1.113 (15/15 ° C), thiab lub refractive index yog 1.5442.Yooj yim soluble hauv cawv thiab ether, yuav luag insoluble hauv dej.

Cov khoom no muaj ib tug me ntsis qab zib fennel aroma thiab feem ntau yog siv nyob rau hauv kev npaj ntawm jasmine, lilac thiab lwm yam flavors, thiab yog haum rau kev npaj ntawm perfumes.Cov khoom no yog cov txuj lom uas tau tso cai los ntawm kuv lub teb chaws GB2760-86.Nws yog tsuas yog siv los npaj flavors xws li vanilla, chocolate, cocoa, almond, thiab txiv duaj.Nws kuj yog siv rau hauv cov organic synthesis thiab ua cov kuab tshuaj.

Los ntawm kev txo qis ntawm anisaldehyde.Cannizzaro reacts nrog anise, formaldehyde thiab sodium hydroxide hauv ethanol los tsim p-methoxybenzyl cawv.

Tom qab cov ethanol tau zoo los ntawm distillation, cov roj txheej tau los ntawm cov tshuaj tiv thaiv yog muab rho tawm nrog benzene, acidified los ntawm kev ntxiv acetic acid, thiab ces neutralized nrog sodium bicarbonate kom tsis muaj zog alkaline.Tom qab ntxuav nrog dej mus rau qhov nruab nrab, cov benzene rov qab los ntawm distillation, thiab cov seem yuav raug rau lub tshuab nqus tsev distillation kom tau txais p-methoxy Benzyl cawv.

Nws ua haujlwm los ntawm stimulating central presynaptic α2-receptors.Nws cov nyhuv antihypertensive zoo ib yam li cov calcium antagonist nifedipine thiab ACE inhibitor captopril.Siv rau qhov tseem ceeb kub siab.