Peb tsis tsuas yog yuav sim peb qhov zoo tshaj plaws los muab cov tuam txhab zoo tshaj plaws rau txhua tus neeg yuav khoom, tab sis kuj npaj tau txais cov lus pom zoo los ntawm peb cov neeg yuav khoom kom zoo zoo 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Pab pawg ntawm peb lub tuam txhab ua ke nrog kev siv cov thev naus laus zis tshiab muab cov khoom lag luam zoo tshaj plaws uas tau txais txiaj ntsig zoo tshaj plaws thiab txaus siab los ntawm peb cov kev cia siab thoob ntiaj teb.
Peb tsis tsuas yog yuav sim peb qhov zoo tshaj plaws los muab cov tuam txhab zoo tshaj plaws rau txhua tus neeg yuav khoom, tab sis kuj npaj tau txais cov lus pom zoo los ntawm peb cov neeg yuav khoom rauTuam Tshoj 2-Cyanobenzyl Bromide Powder thiab Alpha-Bromo-O-Toluonitrile, Peb ntseeg tau tias kev siv tshuab thiab kev pabcuam yog peb lub hauv paus niaj hnub no thiab kev ua haujlwm zoo yuav tsim peb cov phab ntsa txhim khu kev qha rau yav tom ntej.Tsuas yog peb tau zoo dua thiab zoo dua, peb tuaj yeem ua tiav peb cov neeg siv khoom thiab peb tus kheej, ib yam nkaus.Zoo siab txais tos cov neeg muas zaub thoob plaws lo lus hu rau peb kom tau txais kev lag luam ntxiv thiab kev sib raug zoo.Peb ib txwm nyob ntawm no ua haujlwm rau koj qhov kev xav tau thaum twg koj xav tau.
Siv:Intermediate rau Linagliptin.
Siv:Intermediate rau Linagliptin
Executive standard:tus qauv kev lag luam
Assay:98-102%
Sab nrauv:Dawb rau lub teeb daj hmoov
Pob:25kg / nruas
Txhawm rau txheeb xyuas cov linagliptin uas twb muaj lawm thiab nws qhov tseem ceeb nruab nrab 8-bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl -2-quinazolinyl)methyl)-1H-purine- 2,6-dione (11) synthesis txoj kev, nrhiav ib txoj kev hluavtaws haum rau kev tsim khoom.Txoj kev: summarize qhov sib txawv synthetic txoj kev.Cov txiaj ntsig thiab cov lus xaus: Txoj Kev 2.2 muaj cov txheej txheem yooj yim thiab tus nqi qis dua, uas tsim nyog rau kev tsim khoom lag luam.
8-bromo-3,7-dihydro-3-methyl-1H-purine-2,6-dione yog ib qho tseem ceeb nruab nrab ntawm cov synthesis ntawm cov tshuaj hypoglycemic linagliptin.Lub synthesis ntawm 1 siv methyl urea thiab cyanoacetic acid raws li cov ntaub ntawv pib, thiab dhau mus rau 6-kauj ruam kev tshwm sim ntawm condensation, cyclization, nitrosation, txo, cyclization, thiab bromine nrog tag nrho cov txiaj ntsig ntawm 46.3%.Cov qauv ntawm txhua tus neeg nruab nrab tau lees paub los ntawm 1HNMR.
Tam sim no invention muaj feem xyuam rau txoj kev npaj yooj yim ntawm high-purity linagliptin.Quinazoline, qhov nruab nrab tseem ceeb rau kev npaj ib lub lauj kaub ntawm linagliptin 8 bromo 7 (2 butyne 1 puag) 3,7 dihydro 3 methyl 1 [(4 methyl 2 quinazolinyl) methyl] 1H Purine 2,6 dione, qhov nruab nrab yog cais los ntawm filtration, thiab ces reacted nrog (R) 3 aminopiperidine dihydrochloride kom tau txais cov tshuaj uas muaj linagliptin.Tom qab cov tshuaj uas muaj linagliptin tau ua tiav dua, Deliraliptin cov khoom ntshiab.Kev npaj ntawm qhov tseem ceeb nruab nrab ntawm qhov kev tsim kho tam sim no siv txoj hauv kev ib lub lauj kaub, uas yooj yim rau kev khiav lag luam thiab txhim kho cov txiaj ntsig.Tom qab qhov tseem ceeb nruab nrab yog sib cais, nws yog reacted nrog (R) 3 aminopiperidine dihydrochloride, yog li tau txais high-purity linagliptin kuj ua tau raws li qhov yuav tsum tau ntawm zus tau tej cov thiab tshaj tawm cov kev cai ntawm cov tuam txhab tshuaj mus rau qhov loj tshaj plaws.
Peb tsis tsuas yog yuav sim peb qhov zoo tshaj plaws los muab cov tuam txhab zoo tshaj plaws rau txhua tus neeg yuav khoom, tab sis kuj npaj tau txais cov lus pom zoo los ntawm peb cov neeg yuav khoom kom zoo zoo 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Pab pawg ntawm peb lub tuam txhab ua ke nrog kev siv cov thev naus laus zis tshiab muab cov khoom lag luam zoo tshaj plaws uas tau txais txiaj ntsig zoo tshaj plaws thiab txaus siab los ntawm peb cov kev cia siab thoob ntiaj teb.
Zoo zooTuam Tshoj 2-Cyanobenzyl Bromide Powder thiab Alpha-Bromo-O-Toluonitrile, Peb ntseeg tau tias kev siv tshuab thiab kev pabcuam yog peb lub hauv paus niaj hnub no thiab kev ua haujlwm zoo yuav tsim peb cov phab ntsa txhim khu kev qha rau yav tom ntej.Tsuas yog peb tau zoo dua thiab zoo dua, peb tuaj yeem ua tiav peb cov neeg siv khoom thiab peb tus kheej, ib yam nkaus.Zoo siab txais tos cov neeg muas zaub thoob plaws lo lus hu rau peb kom tau txais kev lag luam ntxiv thiab kev sib raug zoo.Peb ib txwm nyob ntawm no ua haujlwm rau koj qhov kev xav tau thaum twg koj xav tau.