Hydroxypyrazolodpyrimidine pyrazolo (3,4-d) pyrimidin-1-ol
Hydroxypyrazolodpyrimidine pyrazolo (3,4-d) pyrimidin-1-ol
Nws yog siv hauv kev kho mob hauv thawj thiab theem nrab Hyperuricemia, tshwj xeeb tshaj yog rau cov neeg mob hyperuricemia, nrog rau cov neeg mob lub raum tsis ua haujlwm, thiab cov neeg mob uas rov muaj dua lossis mob gout, nrog rau cov neeg mob hyperuricemia.Siv rau cov neeg mob Gouty nephropathy los txo cov tsos mob thiab txo qhov tsim ntawm lub raum uric acid pob zeb;pob zeb gout;siv nyob rau hauv uric acid raum pob zeb thiab uric acid raum kab mob.
Cov khoom no thiab nws cov metabolites tuaj yeem cuam tshuam xanthine oxidase, yog li hypoxanthine thiab xanthine tsis tuaj yeem hloov mus rau hauv uric acid, uas yog, cov synthesis ntawm uric acid txo, yog li txo qhov concentration ntawm uric acid hauv cov ntshav thiab txo cov concentration ntawm urate hauv cov ntshav. cov pob txha, Cov pob qij txha thiab ob lub raum, cov tshuaj uas tuaj yeem cuam tshuam cov synthesis ntawm uric acid.Cov khoom no tuaj yeem cuam tshuam kev ua haujlwm ntawm daim siab tshuaj enzymes.
(1).Thawj thiab theem nrab hyperuricemia, tshwj xeeb tshaj yog cov uas muaj uric acid ntau dhau, kuj siv rau hyperuricemia nrog raum tsis txaus;
(2).Rau kev kho mob ntawm gout, haum rau recurrent los yog mob gout.Rau cov neeg mob gouty nephropathy, nws tuaj yeem txo cov tsos mob thiab txo qhov tsim ntawm uric acid pob zeb hauv ob lub raum;
(3).Tophi;
(4).Siv rau uric acid raum pob zeb thiab (los yog) uric acid nephropathy.
Txheem:usp42 ua
Assay:98-102%
Sab nrauv:Dawb los yog yuav luag dawb hmoov
Pob:25kg / hnab
Muaj cov pob txha pob txha tawg, uas tuaj yeem ua rau pancytopenia, thiab cov tshuaj yuav tsum tau txiav yog tias tsim nyog.Haus dej kom ntau thaum noj tshuaj, thiab ua rau cov zis nruab nrab lossis alkaline kom tshem tawm cov kua qaub diuretic.Cov khoom no yuav tsum tau siv tom qab qhov mob ntawm gouty mob caj dab ploj mus (feem ntau li ob lub lis piam tom qab pib).Thaum noj tshuaj, cov duab ntshav thiab daim siab thiab lub raum yuav tsum tau kuaj xyuas tsis tu ncua.
JIN DUN Medical muajISO tsim nyog thiab ua tau raws li GMP cov qauv tsim, ua hauj lwm hauv tsev thiab txawv teb chaws cov kws kho tshuaj synthesis nrog kev nplua nuj los coj lub tuam txhab R & D.
TECHNOL OGY ADVANTAGES
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction.Cryogenic cov tshuaj tiv thaiv (<-78% C)
●Aromatic Heterocyclic Synthesis
● Kev Ruaj Ntseg Tsis Zoo
● Chiral Resolution
●Heck, Suzuki, Negishi, Sonogashira .Gignard Reaction
Cov khoom siv
Peb lub Lab muaj ntau yam kev sim thiab ntsuas cov cuab yeej, xws li: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope ...
Pab neeg R&D
Jindun Kev Kho Mob muaj ib pab pawg kws tshaj lij R & D cov neeg ua haujlwm, thiab ntiav ntau tus kws tshaj lij kev siv tshuaj hauv tsev thiab txawv teb chaws los coj R&D, ua rau peb cov khoom sib xyaw ua kom raug thiab ua tau zoo.
Peb tau pab ntau lub tuam txhab tshuaj hauv tsev sab saum toj, xws liHansoh, Hengrui thiab HEC Pharm.Ntawm no peb yuav qhia ib feem ntawm lawv.
Customzation Case Ib:
CAS Nr .: 110351-94-5
Customzation Case Ob:
CAS Nr .: 144848-24-8
Customzation Case Peb:
CAS Nr .: 200636-54-0
1.Customize New Intermediates lossis APIs.Ib yam li cov ntaub ntawv sib qhia saum toj no, cov neeg siv khoom muaj qhov xav tau tshwj xeeb Intermediates lossis APIs, thiab lawv nrhiav tsis tau cov khoom xav tau hauv khw, ces peb tuaj yeem pab kho.
2.Txheej txheem Optimization rau cov khoom qub.Peb pab neeg yuav pab Optimize thiab txhim kho xws li ntau lawm uas nws cov tshuaj tiv thaiv txoj kev yog qub, ntau lawm nqi yog siab, thiab efficiency yog tsawg.Peb tuaj yeem muab cov ntaub ntawv tag nrho rau kev hloov pauv thev naus laus zis thiab kev txhim kho cov txheej txheem, pab cov neeg siv khoom kom muaj txiaj ntsig ntau dua.
Los ntawm cov hom phiaj tshuaj rau INDs, JIN DUN Kev Kho Mob muab rau kojib-nres tus kheej R & D kev daws teeb meem.
JIN DUN Kev Kho Mob hais kom tsim ib pab neeg nrog kev npau suav, ua cov khoom muaj txiaj ntsig, ua kom zoo, nruj, thiab tawm mus ua ib tus neeg ntseeg siab thiab phooj ywg ntawm cov neeg siv khoom!
![1,4′-Bipiperidine]-1′-carbonyl chloride HCl](http://cdn.globalso.com/jindunchem-med/image211-300x300.png)
