L-Valine
L-Valine
L-Valine yog siv los ua qhov nruab nrab ntawm Valaciclovir.
Valacyclovir yog guanine analogue tshuaj tua kab mob.Nws yog siv nyob rau hauv kev kho mob ntawm herpes simplex thiab herpes zoster kab mob nyob rau hauv kev sib deev kab mob.Cov khoom no yog qhov ua ntej ntawm acyclovir.Nws tau nqus sai sai tom qab kev tswj hwm qhov ncauj thiab hloov pauv sai sai rau hauv acyclovir hauv lub cev.Nws cov nyhuv antiviral yog ua si los ntawm acyclovir.Tom qab acyclovir nkag mus rau hauv cov kab mob herpes, nws sib tw nrog deoxynucleoside rau tus kab mob thymidine deoxynucleoside kinase los yog cell kinase, thiab cov tshuaj yog phosphorylated rau hauv activated acyclic guanosine triphosphate.Raws li lub substrate ntawm tus kab mob replication, acyclovir sib tw nrog deoxyguanine triphosphate rau tus kab mob DNA polymerase, uas inhibits tus kab mob DNA synthesis thiab qhia antiviral nyhuv.Cov tshuaj tiv thaiv kab mob ntawm cov khoom no hauv vivo yog qhov zoo dua li acyclovir, thiab kev kho mob ntawm tus kab mob herpes simplex hom I thiab hom II yog 42.91% thiab 30.13% siab dua acyclovir feem.Nws kuj muaj cov nyhuv curative siab rau tus kab mob varicella zoster.
JIN DUN Medical muajISO tsim nyog thiab ua tau raws li GMP cov qauv tsim, ua hauj lwm hauv tsev thiab txawv teb chaws cov kws kho tshuaj synthesis nrog kev nplua nuj los coj lub tuam txhab R & D.
TECHNOL OGY ADVANTAGES
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction.Cryogenic cov tshuaj tiv thaiv (<-78% C)
●Aromatic Heterocyclic Synthesis
● Kev Ruaj Ntseg Tsis Zoo
● Chiral Resolution
●Heck, Suzuki, Negishi, Sonogashira .Gignard Reaction
Cov khoom siv
Peb lub Lab muaj ntau yam kev sim thiab ntsuas cov cuab yeej, xws li: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope ...
Pab neeg R&D
Jindun Kev Kho Mob muaj ib pab pawg kws tshaj lij R & D cov neeg ua haujlwm, thiab ntiav ntau tus kws tshaj lij kev siv tshuaj hauv tsev thiab txawv teb chaws los coj R&D, ua rau peb cov khoom sib xyaw ua kom raug thiab ua tau zoo.
Peb tau pab ntau lub tuam txhab tshuaj hauv tsev sab saum toj, xws liHansoh, Hengrui thiab HEC Pharm.Ntawm no peb yuav qhia ib feem ntawm lawv.
Customzation Case Ib:
CAS Nr .: 110351-94-5
Customzation Case Ob:
CAS Nr .: 144848-24-8
Customzation Case Peb:
CAS Nr .: 200636-54-0
1.Customize New Intermediates lossis APIs.Ib yam li cov ntaub ntawv sib qhia saum toj no, cov neeg siv khoom muaj qhov xav tau tshwj xeeb Intermediates lossis APIs, thiab lawv nrhiav tsis tau cov khoom xav tau hauv khw, ces peb tuaj yeem pab kho.
2.Txheej txheem Optimization rau cov khoom qub.Peb pab neeg yuav pab Optimize thiab txhim kho xws li ntau lawm uas nws cov tshuaj tiv thaiv txoj kev yog qub, ntau lawm nqi yog siab, thiab efficiency yog tsawg.Peb tuaj yeem muab cov ntaub ntawv tag nrho rau kev hloov pauv thev naus laus zis thiab kev txhim kho cov txheej txheem, pab cov neeg siv khoom kom muaj txiaj ntsig ntau dua.
Los ntawm cov hom phiaj tshuaj rau INDs, JIN DUN Kev Kho Mob muab rau kojib-nres tus kheej R & D kev daws teeb meem.
JIN DUN Kev Kho Mob hais kom tsim ib pab neeg nrog kev npau suav, ua cov khoom muaj txiaj ntsig, ua kom zoo, nruj, thiab tawm mus ua ib tus neeg ntseeg siab thiab phooj ywg ntawm cov neeg siv khoom!
![4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride](http://cdn.globalso.com/jindunchem-med/dc3948321-300x300.jpg)
