Pentamethylene bis[1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dixalate
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Pentamethylene bis[1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dixalate
pentamethylene bis[1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate yog siv los ua qhov nruab nrab ntawm Cisatracurium besylate.
Cisatracurium besylate yog benzene sulfonate ntsev daim ntawv ntawm atracurium.Nws yog ib yam ntawm cov hluavtaws hluavtaws uas tsis yog-depolarizing cov leeg nqaij so nrog nws lub luag haujlwm zoo ib yam li tubocurarine.Nws muaj lub sijhawm pib ntawm 1 feeb thiab lub sijhawm ntev ntawm 15 feeb.Cov koob tshuaj kho mob tsis cuam tshuam rau lub plawv, lub siab thiab lub raum ua haujlwm.Nws kuj tsis muaj khoom tsub zuj zuj.Nws kuj tuaj yeem ua rau muaj kev tso tawm ntawm histamine thaum siv ntau npaum li cas.Rau cov leeg nqaij so lossis kev tswj ua pa yuav tsum tau ua hauv kev phais, piv nrog tam sim no cov chaw kho mob loj cov leeg-txo cov tshuaj loog, cisatracurium besylate tsis metabolized los ntawm daim siab lossis lub raum, thiab muaj cov hlab plawv;nws cov nyhuv ntawm cov leeg so yog 3 npaug zog li atracurium yam tsis muaj kev mob plawv.Cisatracurium besylate feem ntau yog siv rau kev siv tshuaj loog, thiab tuaj yeem siv dav hauv intubation, kho lub siab thiab lub raum tsis ua haujlwm, siv rau hauv kev phais plawv thiab cov neeg laus thiab menyuam yaus.
Piv nrog rau atracurium, cov khoom no tsis muaj kev cuam tshuam ntawm cov tshuaj histamine tso tawm;Txawm li cas los xij, qhov tsis zoo yog tias cov neeg mob lub siab thiab lub raum tsis ua haujlwm yuav tsum tau ceev faj.
Txij li thaum xyoo 1996 thawj zaug thaum cov tshuaj no tau nkag mus rau hauv kev ua lag luam hauv UK, cov teb chaws txawv teb chaws tau maj mam siv nws los hloov vecuronium thiab atracurium ua lub ntsiab ntawm kev kho cov leeg nqaij.
JIN DUN Medical muajISO tsim nyog thiab ua tau raws li GMP cov qauv tsim, ua hauj lwm hauv tsev thiab txawv teb chaws cov kws kho tshuaj synthesis nrog kev nplua nuj los coj lub tuam txhab R & D.
TECHNOL OGY ADVANTAGES
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction.Cryogenic cov tshuaj tiv thaiv (<-78% C)
●Aromatic Heterocyclic Synthesis
● Kev Ruaj Ntseg Tsis Zoo
● Chiral Resolution
●Heck, Suzuki, Negishi, Sonogashira .Gignard Reaction
Cov khoom siv
Peb lub Lab muaj ntau yam kev sim thiab ntsuas cov cuab yeej, xws li: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope ...
Pab neeg R&D
Jindun Kev Kho Mob muaj ib pab pawg kws tshaj lij R & D cov neeg ua haujlwm, thiab ntiav ntau tus kws tshaj lij kev siv tshuaj hauv tsev thiab txawv teb chaws los coj R&D, ua rau peb cov khoom sib xyaw ua kom raug thiab ua tau zoo.
Peb tau pab ntau lub tuam txhab tshuaj hauv tsev sab saum toj, xws liHansoh, Hengrui thiab HEC Pharm.Ntawm no peb yuav qhia ib feem ntawm lawv.
Customzation Case Ib:
CAS Nr .: 110351-94-5
Customzation Case Ob:
CAS Nr .: 144848-24-8
Customzation Case Peb:
CAS Nr .: 200636-54-0
1.Customize New Intermediates lossis APIs.Ib yam li cov ntaub ntawv sib qhia saum toj no, cov neeg siv khoom muaj qhov xav tau tshwj xeeb Intermediates lossis APIs, thiab lawv nrhiav tsis tau cov khoom xav tau hauv khw, ces peb tuaj yeem pab kho.
2.Txheej txheem Optimization rau cov khoom qub.Peb pab neeg yuav pab Optimize thiab txhim kho xws li ntau lawm uas nws cov tshuaj tiv thaiv txoj kev yog qub, ntau lawm nqi yog siab, thiab efficiency yog tsawg.Peb tuaj yeem muab cov ntaub ntawv tag nrho rau kev hloov pauv thev naus laus zis thiab kev txhim kho cov txheej txheem, pab cov neeg siv khoom kom muaj txiaj ntsig ntau dua.
Los ntawm cov hom phiaj tshuaj rau INDs, JIN DUN Kev Kho Mob muab rau kojib-nres tus kheej R & D kev daws teeb meem.
JIN DUN Kev Kho Mob hais kom tsim ib pab neeg nrog kev npau suav, ua cov khoom muaj txiaj ntsig, ua kom zoo, nruj, thiab tawm mus ua ib tus neeg ntseeg siab thiab phooj ywg ntawm cov neeg siv khoom!
