2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate

2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate yog siv los ua qhov nruab nrab ntawm Gemcitabine.
Gemcitabine yog ib qho pyrimidine nucleotide analogue, uas belongs rau cov tshuaj tiv thaiv kab mob metabolic.Nws tuaj yeem tiv thaiv kev nce qib ntawm DNA synthesis hauv ib lub sijhawm, uas yog, S-theem.Nws muaj cov yam ntxwv ntawm dav anticancer spectrum, tshwj xeeb mechanism ntawm kev txiav txim, tsis tshua muaj toxicity, tsis muaj cross resistance nrog rau lwm yam tshuaj chemotherapeutic thiab tsis muaj superposition ntawm toxicity.Niaj hnub no, gemcitabine tau pom zoo siv nyob rau hauv ntau tshaj 90 lub teb chaws, dhau los ua thawj kab tshuaj rau kev kho mob ntawm cov qog nqaij hlav qog nqaij hlav tsis me me thiab "tus qauv kub" rau kev kho mob qog noj ntshav pancreatic.