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5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]- 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h)-ib

5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]- 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h)-ib

Lus piav qhia luv luv:

CAS no: 150322-38-6

Tshuaj muaj pes tsawg leeg: Prasugrel Intermediates


Product Detail

Khoom cim npe

Siv

5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]- 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h)-ib yog siv los ua qhov nruab nrab ntawm Prasugrel.
Prasugrel yog thiophenopyridine antiplatelet tsim los ntawm Eli Lilly thiab daiichisankyo, lub chaw tsim tshuaj Japanese.Nws yog ib qho tshuaj precursor.Nws tsim ib qho active molecule tom qab metabolism los ntawm cytochrome P450 nyob rau hauv lub siab thiab ua ke nrog platelet P2Y12 receptor kom muaj zog tiv thaiv platelet aggregation.Cov kev tshawb fawb soj ntsuam tau ua pov thawj tias 60 mg koob tshuaj muaj cov nyhuv anticoagulant zoo dua li 300 mg tus qauv koob tshuaj thiab 600 mg nce koob tshuaj clopidogrel, uas tuaj yeem txo cov kev pheej hmoo ntawm plawv nres, mob stroke thiab tuag vim mob plawv los ntawm 20%, thiab muaj txiaj ntsig sai. , zoo curative nyhuv, zoo tshuaj kuj thiab bioavailability, thiab tsawg toxicity.

Resource-integrated Product Line

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Daim ntawv pov thawj

JIN DUN Medical muajISO tsim nyog thiab ua tau raws li GMP cov qauv tsim, ua hauj lwm hauv tsev thiab txawv teb chaws cov kws kho tshuaj synthesis nrog kev nplua nuj los coj lub tuam txhab R & D.

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Qhov zoo ntawm Kev Kho Mob Customization

TECHNOL OGY ADVANTAGES
● High Pressure Catalytic Hydrogenation .High Pressure Hydrogenolysis Reaction.Cryogenic cov tshuaj tiv thaiv (<-78% C)
●Aromatic Heterocyclic Synthesis
● Kev Ruaj Ntseg Tsis Zoo
● Chiral Resolution
●Heck, Suzuki, Negishi, Sonogashira .Gignard Reaction

JIN DUN R&D

Cov khoom siv

Peb lub Lab muaj ntau yam kev sim thiab ntsuas cov cuab yeej, xws li: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope ...

Pab neeg R&D

Jindun Kev Kho Mob muaj ib pab pawg kws tshaj lij R & D cov neeg ua haujlwm, thiab ntiav ntau tus kws tshaj lij kev siv tshuaj hauv tsev thiab txawv teb chaws los coj R&D, ua rau peb cov khoom sib xyaw ua kom raug thiab ua tau zoo.

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Case-Sib koom

Peb tau pab ntau lub tuam txhab tshuaj hauv tsev sab saum toj, xws liHansoh, Hengrui thiab HEC Pharm.Ntawm no peb yuav qhia ib feem ntawm lawv.

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Customzation Case Ib:

CAS Nr .: 110351-94-5

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Customzation Case Ob:

CAS Nr .: 144848-24-8

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Customzation Case Peb:

CAS Nr .: 200636-54-0

Kev koom tes hom

1.Customize New Intermediates lossis APIs.Ib yam li cov ntaub ntawv sib qhia saum toj no, cov neeg siv khoom muaj qhov xav tau tshwj xeeb Intermediates lossis APIs, thiab lawv nrhiav tsis tau cov khoom xav tau hauv khw, ces peb tuaj yeem pab kho.

2.Txheej txheem Optimization rau cov khoom qub.Peb pab neeg yuav pab Optimize thiab txhim kho xws li ntau lawm uas nws cov tshuaj tiv thaiv txoj kev yog qub, ntau lawm nqi yog siab, thiab efficiency yog tsawg.Peb tuaj yeem muab cov ntaub ntawv tag nrho rau kev hloov pauv thev naus laus zis thiab kev txhim kho cov txheej txheem, pab cov neeg siv khoom kom muaj txiaj ntsig ntau dua.

Los ntawm cov hom phiaj tshuaj rau INDs, JIN DUN Kev Kho Mob muab rau kojib-nres tus kheej R & D kev daws teeb meem.

JIN DUN Kev Kho Mob hais kom tsim ib pab neeg nrog kev npau suav, ua cov khoom muaj txiaj ntsig, ua kom zoo, nruj, thiab tawm mus ua ib tus neeg ntseeg siab thiab phooj ywg ntawm cov neeg siv khoom!


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